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SML2023

Sigma-Aldrich

UCSF924NC

≥98% (HPLC)

Synonym(s):

6-Methyl-2-((3-(pyridin-4-yl)propylamino)methyl)quinolin-4(1H)-one

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About This Item

Empirical Formula (Hill Notation):
C19H21N3O
CAS Number:
1434696-12-4
Molecular Weight:
307.39
UNSPSC Code:
51111800
NACRES:
NA.77
Pricing and availability is not currently available.

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

CC1=CC2=C(NC(CNCCCC3=CC=NC=C3)=CC2=O)C=C1

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Show Differences

1 of 4

This Item
SML2022SML0778SML2221
UCSF924NC ≥98% (HPLC)

SML2023

UCSF924NC

UCSF924 ≥98% (HPLC)

SML2022

UCSF924

UNC1999 ≥98% (HPLC)

SML0778

UNC1999

CU-CPT9a ≥98% (HPLC)

SML2221

CU-CPT9a

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 15 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

color

white to beige

color

white to beige

color

white to beige

color

white to beige

Biochem/physiol Actions

Negative control for the dopamine D4 receptor (DRD4) partial agonist UCSF924.
UCSF924NC (Compound 9-6-16; ZINC000091707446) is the recommended negative control compound for the high-affinity dopamine D4 receptor (DRD4) partial agonist UCSF924 (Compound 9-6-24; ZINC000091726127). UCSF924NC exhibits a 1/2500-fold reduced D4 affinity when compared with that of UCSF924.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Sheng Wang et al.
Science (New York, N.Y.), 358(6361), 381-386 (2017-10-21)
Dopamine receptors are implicated in the pathogenesis and treatment of nearly every neuropsychiatric disorder. Although thousands of drugs interact with these receptors, our molecular understanding of dopaminergic drug selectivity and design remains clouded. To illuminate dopamine receptor structure, function, and

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