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Key Documents

SAB2501818

Sigma-Aldrich

Anti-KDM2A antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

CXXC8, DKFZp434M1735, FBL11, lysine (K)-specific demethylase 2A

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

goat

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human, rat, pig, mouse, canine, bovine

technique(s)

indirect ELISA: suitable
western blot: suitable

UniProt accession no.

Q9Y2K7

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... KDM2A(22992)

Immunogen

Peptide with sequence C-PRKDRQVHLTHFELE, from the internal region of the protein sequence according toNP_036440.1

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0899P1
10899P1

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Charles Hernandez et al.
Cell stem cell, 23(3), 396-411 (2018-08-28)
As somatic cells are converted into induced pluripotent stem cells (iPSCs), their chromatin is remodeled to a pluripotent configuration with unique euchromatin-to-heterochromatin ratios, DNA methylation patterns, and enhancer and promoter status. The molecular machinery underlying this process is largely unknown.
Yongkun Wang et al.
Artificial cells, nanomedicine, and biotechnology, 47(1), 2891-2899 (2019-07-17)
JHDM1A participates in cancer development via demethylate dimethyl histone H3 lysine 36 (H3K36me2). p300 is an intrinsic acetyltransferase. This study explored the acetyltransferase activity of p300 on JHDM1A and analyzed the JHDM1A acetylation on H3K36me2 demethylation in osteosarcoma. Co-immunoprecipitation (CoIP)
Lin-Lin Cao et al.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 31(5), 797-805 (2018-06-29)
Colorectal cancer (CRC) is one of the most common malignancies worldwide, and new treatment strategies for CRC are required because of the existing chemotherapy resistance. Iron chelators, which have been used widely for the treatment of iron-overload disease, were reported
Dijana Lađinović et al.
Nucleus (Austin, Tex.), 8(5), 563-572 (2017-08-18)
Histone modifications have a profound impact on the chromatin structure and gene expression and their correct establishment and recognition is essential for correct cell functioning. Malfunction of histone modifying proteins is associated with developmental defects and diseases and detailed characterization

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