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Key Documents

EMU046551

MISSION^® esiRNA

Name: MISSION<SUP>®</SUP> esiRNA
Brand: SIGMA

targeting mouse Tgif1

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About This Item

UNSPSC Code:

41105324

NACRES:

NA.51

description

Quality Level

100

product line

MISSION^®

form

lyophilized powder

esiRNA cDNA target sequence

GCTGAGAAAGGATGGCAAAGATCCAAATCAGTTCACGATTTCCCGCCGTGGGGCCAAGATTTCAGAAGCTAGCTCTATTGAAGCTGCAATGGGTATCAAAAACTTCATGCCAACTCTAGAAGAGAGCCCATTTCATTCCTGCGTAGTTGGACCCAACCCAACCCTAGGGAGACCAGTGTCTCCCAAACCTCCCTCCCCAGGATCCATTTTGGCTCGCCCGTCAGTGATCTGCCATACCACTGTGACTGCATTGAAGGATGGGCCTTTCTCTCTCTGTCAGCCGATTGGTGTGGGACAGAGTACAGATGTACCGCAAATAGCACCCAGCAACTTTACAGACACCTCTCTCGTGTACCCAGAGGACACTTGCAAATCTGGACCCAGTCCAAACCCTCAGAGTGGTC

Ensembl | mouse accession no.

ENSMUSG00000047407

NCBI accession no.

NM_009372

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... TGIF1(21815) , Tgif1(21815)

Related Categories

MISSION® esiRNA

Oligos, qPCR Probes & Peptides

General description

MISSION^® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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TGIF1 Gene Silencing in Tendon-Derived Stem Cells Improves the Tendon-to-Bone Insertion Site Regeneration.

Liyang Chen et al.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 37(6), 2101-2114 (2015-11-26)

The slow healing process of tendon-to-bone junctions can be accelerated via implanted tendon-derived stem cells (TDSCs) with silenced transforming growth interacting factor 1 (TGIF1) gene. Tendon-to-bone insertion site is the special form of connective tissues derivatives of common connective progenitors

Silencing of TGIF1 in bone mesenchymal stem cells applied to the post-operative rotator cuff improves both functional and histologic outcomes.

Jie Li et al.

Journal of molecular histology, 46(3), 241-249 (2015-03-19)

Stem cells have long been hypothesized to improve outcomes following rotator cuff repair. However, these cells must be signaled in order to do so. TGIF1 is a transcription factor that has been found to be down-regulated in cells involved in

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