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MES monohydrate

EMPROVE® EVOLVE

Pharma Manufacturing

Synonym(s):

MES, 2-(N-Morpholino)ethanesulfonic acid, 4-Morpholineethanesulfonic acid monohydrate

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About This Item

Linear Formula:
C6H13NO4S · H2O
CAS Number:
145224-94-8
Molecular Weight:
213.25
Beilstein:
6350956
MDL number:
MFCD00149409
UNSPSC Code:
12161700

biological source

synthetic

Quality Level

400

product line

EMPROVE® EVOLVE

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

Endotoxin, microbial, and trace metals, tested

pH

5.5-6.7

useful pH range

5.5-6.7

pKa (25 °C)

6.1

pKa 

6.1

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Application

MES is a biological buffer often referred to as a “Good′s” buffer .The pKa of MES is 5.96 which makes MES an ideal candidate for cell culture media and protein based buffer formulations to maintain a stable environment in solution. MES is considered to be non-toxic to culture cell lines, highly water soluble and provides high solution clarity.MES is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream), and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins, blood components and growth factors.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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