78445

Tetrahydrofuran

analytical standard

• Synonym(s): Butylene oxide, Oxolane, Tetramethylene oxide
• Empirical Formula (Hill Notation): C₄H₈O
• CAS Number: 109-99-9
• Molecular Weight: 72.11
• Beilstein: 102391
• EC Number: 203-726-8
• MDL number: MFCD00005356
• UNSPSC Code: 12191501
• PubChem Substance ID: 329768151
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• vapor density: 2.5 (vs air)
• vapor pressure: 114 mmHg ( 15 °C); 143 mmHg ( 20 °C)
• Assay: ≥99.9% (GC)
• autoignition temp.: 610 °F
• shelf life: limited shelf life, expiry date on the label
• contains: ~0.025% 2,6-di-tert.-butyl-4-methylphenol as stabilizer
• expl. lim.: 1.8-11.8 %
• technique(s): HPLC: suitable; gas chromatography (GC): suitable

Description

General description

Tetrahydrofuran (THF) is a saturated cyclic ether. Its potential use as a biofuel for internal combustion engines is investigated.

Tetrahydrofuran is an important basic chemical compound, which belongs to the category of 5-membered heterocycles.

This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food. Find all available reference materials for compounds listed in 10/2011 here

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Tetrahydrofuran may be used as an extraction solvent for the determination of pesticide residues in olive oil and phthalates in toys and child care articles by chromatography techniques.

Tetrahydrofuran may find application as a solvent in the synthesis of (S)-2-(1-pyrrolidinylmethyl)pyrrolidine. It is also an excellent solvent for sodium diisopropylamide, which can find applications as an effective base for the isomerization of alkenes and metalation of 1,4-dienes.

Safety Information

• Pictograms: GHS02,GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H302,H319,H335,H336,H351
• Precautionary Statements: P202 - P210 - P233 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Target Organs: Central nervous system, Respiratory system
• Supplementary Hazards: EUH019
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): -6.2 °F - closed cup
• Flash Point(C): -21.2 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves