64340

DL-Methionine

≥99.0% (NT)

• Synonym(s): (±)-2-Amino-4-(methylmercapto)butyric acid, DL-2-Amino-4-(methylthio)butanoic acid
• Linear Formula: CH₃SCH₂CH₂CH(NH₂)COOH
• CAS Number: 59-51-8
• Molecular Weight: 149.21
• Beilstein: 636185
• EC Number: 200-432-1
• MDL number: MFCD00063096
• UNSPSC Code: 12352209
• PubChem Substance ID: 329759959
• NACRES: NA.26

Properties

• Product Name: DL-Methionine, ≥99.0% (NT)
• Quality Level: 200
• Assay: ≥99.0% (NT)
• form: powder or crystals
• optical activity: [α]/D, c = 5 in 5 M HCl (inactive)
• concentration: 5% in 5 M HCl
• ign. residue: ≤0.05%
• color: white
• mp: 280 °C (dec.) (lit.)
• solubility: 5 M HCl: 1 g/10 mL, clear, colorless to almost colorless
• suitability: corresponds for TLC
• application(s): peptide synthesis
• SMILES string: CSCCC(N)C(O)=O
• InChI: 1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)
• InChI key: FFEARJCKVFRZRR-UHFFFAOYSA-N

Description

Application

DL-Methionine has been used to study the susceptibility of methionine to oxidation during the development of monoclonal antibodies.

Biochem/physiol Actions

Methionine is an essential amino acid which acts a precursor for transmethylation and transsulfuration. In proteins, L-methionine is the biologically active form. D-methionine is converted to L-methionine by enzymes in the body. The adenosylation of methionine results in the formation of S-adenosyl-L-methionine (SAM), which serves as a methyl donor to various substances. L-Methionine′s metabolic product glutathione is known to regulate immune response and has antiviral action.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves