319236

Phenolphthalein solution

0.5 wt. % in ethanol: water (1:1)

• Synonym(s): C₂0H₁₄O₄; Phthalin;3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-one
• Empirical Formula (Hill Notation): C₂₀H₁₄O₄
• CAS Number: 77-09-8
• Molecular Weight: 318.32
• Beilstein: 284423
• MDL number: MFCD00005913
• UNSPSC Code: 12171500
• PubChem Substance ID: 24859151
• NACRES: NA.47

Properties

• form: liquid
• Quality Level: 200
• concentration: 0.5 wt. % in ethanol: water (1:1)
• technique(s): titration: suitable
• color: colorless
• visual transition interval: 8.0-10, colorless to red
• mp: -35 °C
• density: 0.918 g/mL at 25 °C
• λmax: 552 nm
• application(s): diagnostic assay manufacturing; hematology; histology

Description

General description

Phenolphthalein is an acid base indicator. It is a weak acid, which is colorless in acidic solution and turns puce pink in alkaline solution.[1] Phenolphthalein is genotoxic. It might cause oxidative damage and binds to estrogen receptors.[2]

Phenolphthalein solution is a synthetic indicator. It is colorless in acidic and neutral conditions. Phenolphthalein gives pink color when added to a base, therefore it is considered as a base indicator.[3]

Application

Phenolphthalein solution has been used to measure total titratable acids by titration method.[4]

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Warning
• Hazard Statements: H226,H319
• Precautionary Statements: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 3
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 75.2 °F - closed cup
• Flash Point(C): 24 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves