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Merck

319236

Sigma-Aldrich

Phenolphthalein solution

0.5 wt. % in ethanol: water (1:1)

Synonym(s):

C20H14O4; Phthalin;3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-one

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About This Item

Empirical Formula (Hill Notation):
C20H14O4
CAS Number:
Molecular Weight:
318.32
Beilstein:
284423
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

Pricing and availability is not currently available.

form

liquid

Quality Level

concentration

0.5 wt. % in ethanol: water (1:1)

technique(s)

titration: suitable

color

colorless

visual transition interval

8.0-10, colorless to red

mp

-35 °C

density

0.918 g/mL at 25 °C

λmax

552 nm

application(s)

diagnostic assay manufacturing
hematology
histology

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This Item
L702272764440469
technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

-

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200

solubility

water: 100 mg/mL, clear, colorless

solubility

water: 50 mg/mL, clear, colorless

solubility

-

solubility

water: soluble(lit.)

form

powder

form

powder or crystals

form

powder or crystals

form

solid

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

-

General description

Phenolphthalein is an acid base indicator. It is a weak acid, which is colorless in acidic solution and turns puce pink in alkaline solution.[1] Phenolphthalein is genotoxic. It might cause oxidative damage and binds to estrogen receptors.[2]
Phenolphthalein solution is a synthetic indicator. It is colorless in acidic and neutral conditions. Phenolphthalein gives pink color when added to a base, therefore it is considered as a base indicator.[3]

Application

Phenolphthalein solution has been used to measure total titratable acids by titration method.[4]

Pictograms

FlameExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

75.2 °F - closed cup

Flash Point(C)

24 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Charu Maini
Headstart Science (CCE), 7 (2017)
Cytokinin Treatment Modifies Litchi Fruit Pericarp Anatomy Leading to Reduced Susceptibility to Post-harvest Pericarp Browning
Fahima A, et al.
Plant Science (2019)
Phenolphthalein laxatives and risk of cancer
Coogan PF, et al.
Journal of the National Cancer Institute, 92(23), 1943-1944 (2000)
Physical Chemistry: Understanding our Chemical World (2008)
Amit Fahima et al.
Plant science : an international journal of experimental plant biology, 283, 41-50 (2019-05-28)
Litchi (Litchi chinensis Sonn.) is a subtropical fruit known for its attractive red pericarp color, semi-translucent white aril and unique flavor and aroma. Rapid post-harvest pericarp browning strictly limits litchi fruit marketing. In the current research, we hypothesized that modification

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