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890820P

Avanti

18:0 DAP

Avanti Research™ - A Croda Brand 890820P, powder

Synonym(s):

1,2-distearoyl-3-dimethylammonium-propane

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About This Item

Empirical Formula (Hill Notation):
C41H81NO4
CAS Number:
121315-93-3
Molecular Weight:
652.09
UNSPSC Code:
12352211
NACRES:
NA.25
Pricing and availability is not currently available.

form

powder

packaging

pkg of 1 × 25 mg (890820P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 890820P

lipid type

transfection
cationic lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H]C(CN(C)C)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O

InChI

1S/C41H81NO4/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-40(43)45-38-39(37-42(3)4)46-41(44)36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h39H,5-38H2,1-4H3

InChI key

RVBUSVJSKGVQQS-UHFFFAOYSA-N

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18:0 DAP Avanti Research™ - A Croda Brand 890820P, powder

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14:0 DAP Avanti Research™ - A Croda Brand 890840P, powder

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18:0 DAP Avanti Research™ - A Croda Brand 890820C

890820C

18:0 DAP

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

packaging

pkg of 1 × 25 mg (890820P-25mg)

packaging

pkg of 1 × 200 mg (890830P-200mg), pkg of 1 × 25 mg (890830P-25mg)

packaging

pkg of 1 × 25 mg (890840P-25mg)

packaging

pkg of 1 × 2.5 mL (890820C-25mg)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

form

powder

form

powder

form

powder

form

liquid

lipid type

transfection
cationic lipids

lipid type

transfection
cationic lipids

lipid type

cationic lipids
transfection

lipid type

transfection
cationic lipids

Application

1,2-distearoyl-3-dimethylammonium-propane (18:0 DAP) might be used to formulate lipid nanoparticles (LNPs) and to test its efficiency of packaging mRNA into an LNP.[1] It might also be used in the preparation of “bubble liposomes” (BLs).[2]

Biochem/physiol Actions

1,2-distearoyl-3-dimethylammonium-propane (18:0 DAP) is a cationic lipid and serves as a pH-sensitive transfection reagent.

Packaging

5 mL Clear Glass Sealed Ampule (890820P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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    Yoko Endo-Takahashi et al.
    Biomaterials, 34(11), 2807-2813 (2013-01-25)
    We have developed polyethyleneglycol (PEG)-modified liposomes (Bubble liposomes; BLs) that entrap ultrasound (US) contrast gas, and we have reported that the combination of BLs and US exposure was an effective tool for delivering pDNA and siRNA in vitro and in

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