PP0520

GlycoProfile^™ 2-AB Labeling Kit

• Synonim(y): Zestaw do znakowania 2-AB
• Kod UNSPSC: 12352200
• NACRES: NA.32

Właściwości

• Poziom jakości: 200

Opis

Opis ogólny

The GlycoProfile^™ labeling kits are designed for efficient labeling of N-linked, O-linked, and glycosyl­phosphatidyl­inositol (GPI) anchored glycans with either 2-aminobenzamide (2-AB) or 2-aminobenzoic acid (anthranilic acid; 2-AA). These small fluorophores increase the spectral absorption of glycans, improving the detection of labeled glycans by HPAE (high-performance anion exchange chromatography), HPLC, and ESI-MS (electrospray mass spectroscopy) methods. Binding is robust and the resulting dye-glycan conjugates are stable, with no degradation during post-labeling analysis.

Zastosowanie

GlycoProfile^™ 2-AB Labeling Kit has been used for the labelling of N-linked glycans from human IgG, Bovine fetuin, and human epididymis protein 4. It has also been used for labelling free oligosaccharides from mouse spleen.

While 2-AB is slightly less sensitive than 2-AA, it is suitable for downstream glycan analysis by HPAE, HPLC and ESI-MS. Although suitable for the same applications, 2-AA is better suited for SDS-PAGE.

Informacje prawne

Labeling of glycans with 2-AB is covered under US Patent No. 5,747,347 and its foreign equivalents.

GlycoProfile is a trademark of Sigma-Aldrich Co. LLC

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Tylko elementy zestawu

• 2-AB Labeling Reagent 2 x 5
• Dimethyl sulfoxide (DMSO) 2 x 350
• Acetic acid, glacial 2 x 200
• Reductant (sodium cyanoborohydride) 2 x 6

Informacja o środkach bezpieczeństwa

• Piktogramy: GHS02,GHS06,GHS05,GHS09
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H228,H260,H300 + H310 + H330,H314,H410
• Zwroty wskazujące środki ostrożności: P210 - P231 + P232 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Klasyfikacja zagrożeń: Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Flam. Sol. 1 - Skin Corr. 1A - Water-react 1
• Zagrożenia dodatkowe: EUH032
• Kod klasy składowania: 4.3 - Hazardous materials which set free flammable gases upon contact with water