L0130

β-Lactoglobulin from bovine milk

≥90% (PAGE), lyophilized powder

• Synonym(s): β-LG, Bos d 5, beta-LG
• CAS Number: 9045-23-2
• EC Number: 232-928-9
• MDL number: MFCD00130635
• UNSPSC Code: 12352202
• NACRES: NA.61

Properties

• biological source: bovine milk
• Quality Level: 300
• Assay: ≥90% (PAGE)
• form: lyophilized powder
• UniProt accession no.: P02754
• storage temp.: 2-8°C
• Gene Information: bovine ... LGB(280838)

Description

General description

A member of the lipocalin family, β-Lactoglobulin (βLg) is a small protein of 162 amino acids with a molecular mass of ∼18,400 Da. It features an eight-stranded β-barrel (strands A-H) succeeded by a three-turn a-helix and a final β-strand (strand I) that forms part of the dimerization interface.

Milk from dairy cows contains the protein β-lactoglobulin (BLG). It naturally occurs in a number of genetic variants, and the most prevalent bovine variants are BLG A and BLG B.

Application

β-Lactoglobulin from bovine milk was used to test the allergen-responsive CD4+ CD25+ regulatory T cells in children who have outgrown cow′s milk allergy. It is also used to test the competitive displacement of β-lactoglobulin by Tween 20 from oil-water and air-water interfaces.

Other Notes

Contains β-lactoglobulins A and B which can be isolated chromatographically.

Quality

May not contain folate binding protein; not recommended for folate analysis.

Preparation Note

Crystallized

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves