E4378

Ethylene glycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid

≥97.0%

• Synonym(s): EGTA, Egtazic acid, Ethylene-bis(oxyethylenenitrilo)tetraacetic acid, Glycol ether diamine tetraacetic acid
• Linear Formula: [-CH₂OCH₂CH₂N(CH₂CO₂H)₂]₂
• CAS Number: 67-42-5
• Molecular Weight: 380.35
• Beilstein: 1717370
• EC Number: 200-651-2
• MDL number: MFCD00004291
• UNSPSC Code: 12352106
• PubChem Substance ID: 24278421
• NACRES: NA.77

Properties

• biological source: synthetic (organic)
• Quality Level: 400
• Assay: ≥97.0%
• form: powder
• reaction suitability: reagent type: chelator
• loss: ≤1.0% loss on drying
• mp: 241 °C (dec.) (lit.)
• solubility: 1 M NaOH: 1.1 g/10 mL, clear, colorless
• storage temp.: room temp
• SMILES string: OC(=O)CN(CCOCCOCCN(CC(O)=O)CC(O)=O)CC(O)=O
• InChI: 1S/C14H24N2O10/c17-11(18)7-15(8-12(19)20)1-3-25-5-6-26-4-2-16(9-13(21)22)10-14(23)24/h1-10H2,(H,17,18)(H,19,20)(H,21,22)(H,23,24)
• InChI key: DEFVIWRASFVYLL-UHFFFAOYSA-N

Description

Application

A chelating agent useful for the determination of calcium in the presence of magnesium.

Ethylene glycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid has been used as a component of:

• ice-cold cardioplegia solution for transverse aortic constriction in rats
• ice-cold lysis buffer for protein extraction and whole extract cells
• buffer A, B and, C for the extraction of mitochondria from HEK293F cells

Biochem/physiol Actions

Ethylene glycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid A is a chelating agent used for the determination of calcium in the presence of magnesium.

Physical properties

solubility in water increases with pH

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves