P6280

Pyridoxine hydrochloride

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

• Synonym(s): Adermine hydrochloride, PN HCl, Pyridoxol hydrochloride, Vitamin B₆ hydrochloride
• Empirical Formula (Hill Notation): C₈H₁₁NO₃ · HCl
• CAS Number: 58-56-0
• Molecular Weight: 205.64
• Beilstein: 3632435
• EC Number: 200-386-2
• MDL number: MFCD00012807
• UNSPSC Code: 12161900
• eCl@ss: 34058008
• PubChem Substance ID: 24898752
• NACRES: NA.21

Properties

• product line: BioReagent
• Quality Level: 200
• Assay: ≥98% (HPLC)
• form: powder
• mol wt: M_w 205.64 g/mol
• technique(s): cell culture | insect: suitable; cell culture | mammalian: suitable; cell culture | plant: suitable
• color: white to off-white
• mp: 214-215 °C (lit.)
• solubility: water: soluble 50 mg/mL, clear, colorless to faintly yellow
• application(s): agriculture
• SMILES string: Cl[H].Cc1ncc(CO)c(CO)c1O
• InChI: 1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H
• InChI key: ZUFQODAHGAHPFQ-UHFFFAOYSA-N

Description

General description

Pyridoxine is a water-soluble vitamin that exists in six forms called, pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phosphate, pyridoxine 5′-phosphate, and pyridoxal 5′-phosphate. 

Application

Pyridoxine hydrochloride has been used:

• as a vitamin component in a chemically defined diet with balanced metal content for metal depletion studies
• as a component of chemically defined medium (CDM) to culture Staphylococcus aureus WSPPA
• as a vitamin to study the impact of protein expression and post-translational modifications specifically charge heterogeneity

Biochem/physiol Actions

Pyridoxine functions as an essential coenzyme for amino acid, carbohydrate, and lipid metabolism. Pyridoxine deficiency is associated with peripheral neuropathy, microcytic anemia, and electroencephalographic abnormalities. It is implicated in a wide range of biochemical reactions that affect cellular processes. Pyridoxine serves as an alternative to pyridoxal which can degrade in media.

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H318
• Precautionary Statements: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves