47673

Formaldehyde solution

tested according to Ph. Eur.

• Synonym(s): Formaldehydi solutio 35 per centum, Formalin
• Linear Formula: HCHO
• CAS Number: 50-00-0
• Molecular Weight: 30.03
• Beilstein: 1209228
• MDL number: MFCD00003274
• UNSPSC Code: 12352114
• PubChem Substance ID: 329757334
• NACRES: NA.25

Properties

• Agency: USP/NF; tested according to Ph. Eur.
• Quality Level: 200
• vapor density: 1.03 (vs air)
• vapor pressure: 52 mmHg ( 37 °C)
• form: liquid
• autoignition temp.: 572 °F
• contains: 9.0-15.0 % (v/v) methanol as stabilizer
• concentration: 25-50%
• solubility: water: soluble
• density: 1.09 g/mL at 25 °C (lit.)
• suitability: suitable for manufacturing use (Laboratory chemicals)
• SMILES string: [H]C([H])=O
• InChI: 1S/CH2O/c1-2/h1H2
• InChI key: WSFSSNUMVMOOMR-UHFFFAOYSA-N

Description

Application

Formaldehyde solution has been used to fix labeled cells during flow cytometry.

Biochem/physiol Actions

Formaldehyde is the simplest aldehyde that denatures the bihelical regions of RNA and converts the polynucleotides into random coils. It is a genotoxic substance that significantly induces DNA-protein crosslinks (DPC), sister-chromatid exchanges, micronuclei formation and leads to cytotoxicity. It also induces tumors in the nasal epithelium of rats and supposed to be a human carcinogen.

Caution

may become turbid on storage

Safety Information

• Pictograms: GHS02,GHS06,GHS08,GHS05
• Signal Word: Danger
• Hazard Statements: H226,H301 + H311,H314,H317,H330,H335,H341,H350,H370
• Precautionary Statements: P202 - P210 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 1 - STOT SE 3
• Target Organs: Eyes,Central nervous system, Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 133.0 °F - closed cup
• Flash Point(C): 56.11 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves