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SML2902

Sigma-Aldrich

LP-922056

≥98% (HPLC)

Synonym(s):

2-((6-Chloro-7-cyclopropylthieno[3,2-d]pyrimidin-4-yl)thio)acetic acid, LP 922056

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About This Item

Empirical Formula (Hill Notation):
C11H9ClN2O2S2
CAS Number:
1365060-22-5
Molecular Weight:
300.78
MDL number:
MFCD22572369
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

[s]1c2c(ncnc2SCC(=O)O)c(c1Cl)C3CC3

InChI

1S/C11H9ClN2O2S2/c12-10-7(5-1-2-5)8-9(18-10)11(14-4-13-8)17-3-6(15)16/h4-5H,1-3H2,(H,15,16)

InChI key

LJYRIWUQISYYHA-UHFFFAOYSA-N

Biochem/physiol Actions

LP-922056 is an orally active, potent and selective NOTUM pectinacetylesterase inhibitor that activates Wnt signaling. LP-922056 stimulates endocortical bone formation in rodents and in humanized NOTUM mouse line.
orally active, potent and selective NOTUM pectinacetylesterase inhibitor that activates Wnt signaling and stimulates bone formation

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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