SCP0222
Prodynorphin 228-256 porcine / Dynorphin B 29 Leumorphin
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About This Item
Empirical Formula (Hill Notation):
C161H236N42O48
Molecular Weight:
3527.85
UNSPSC Code:
12352200
NACRES:
NA.77
Recommended Products
Assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥75%
storage condition
protect from light
storage temp.
−20°C
Amino Acid Sequence
Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr-Arg-Ser-Gln-Glu-Asp-Pro-Asn-Ala-Tyr-Tyr-Glu-Glu-Leu-Phe-Asp-Val
Application
Leumorphin and prodynorphin are endogenous opioid polypeptide hormones used to study opioid signaling and opioid peptide metabolic processing.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Brigitte L Kieffer et al.
Progress in neurobiology, 66(5), 285-306 (2002-05-17)
The endogenous opioid system consists of three opioid peptide precursor genes encoding enkephalins (preproenkephalin, Penk), dynorphins (preprodynorphin, Pdyn) and beta-endorphin (betaend), proopiomelanocortin (POMC) and three receptor genes encoding mu-opiod receptor (MOR), delta-opiod receptor (DOR) and kappa-opiod receptor (KOR). In the
Patrice G Guyenet et al.
Clinical and experimental pharmacology & physiology, 29(3), 238-242 (2002-03-22)
1. The present article reviews several aspects of opioid signalling in the rostral ventrolateral medulla (RVLM) and their implications for the neural control of blood pressure. 2. In the RVLM, preproenkephalin (PPE) mRNA is expressed by bulbospinal cells that are
Invertebrate opiate immune and neural signaling.
George B Stefano et al.
Advances in experimental medicine and biology, 521, 126-147 (2003-03-06)
S R Ojeda et al.
Recent progress in hormone research, 55, 197-223 (2000-10-19)
It is becoming increasingly clear that astroglial cells are active participants in the process by which information is generated and disseminated within the central nervous system (CNS). In the hypothalamus, astrocytes regulate the secretory activity of neuroendocrine neurons. They contribute
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