SAB4702041

Monoclonal Anti-HLA-DR APC-Cyanine7 produced in mouse

• UNSPSC Code: 12352203

Properties

• conjugate: APC-Cy7 conjugate
• Quality Level: 100
• antibody product type: primary antibodies
• clone: L243, monoclonal
• form: buffered aqueous solution
• species reactivity: ( Non-human primates), ( Human), dog
• technique(s): flow cytometry: suitable
• isotype: IgG2aκ
• storage temp.: 2-8°C
• target post-translational modification: unmodified

Description

General description

HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.

Specificity

The mouse monoclonal antibody L243 recognizes specifically an extracellular epitope on HLA-DR molecules, both peptide-loaded and empty.

Immunogen

Human B lymphocytes

Physical form

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preparation Note

Purified antibody is conjugated with activated tandem dye of allophycocyanin-cyanine 7 (APC-Cy7) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Storage and Stability

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Other Notes

The antibody solution should be gently mixed before use.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable