1000521

Acarbose

United States Pharmacopeia (USP) Reference Standard

• 동의어(들): 4",6"-Dideoxy-4"-([1S]-[1,4,6/5]-4,5,6-trihydroxy-3-hydroxymethyl-2-yclohexenylamino)-maltotriose
• 실험식(Hill 표기법): C₂₅H₄₃NO₁₈
• CAS Number: 56180-94-0
• Molecular Weight: 645.60
• MDL number: MFCD00869592
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329748872
• NACRES: NA.24

속성

• Grade: pharmaceutical primary standard
• API family: acarbose
• 양식: solid
• 제조업체/상표: USP
• 응용 분야: pharmaceutical (small molecule)
• 형식: neat
• 저장 온도: 2-8°C
• SMILES string: C[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O[C@@H]2CO)O[C@H]3[C@H](O)[C@@H](O)[C@H](O)O[C@@H]3CO)[C@H](O)[C@@H](O)[C@@H]1N[C@H]4C=C(CO)[C@@H](O)[C@H](O)[C@H]4O
• InChI: 1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-/m1/s1
• InChI key: XUFXOAAUWZOOIT-SXARVLRPSA-N
• 유전자 정보: human ... AMY2A(279) , MGAM(8972)

설명

일반 설명

Acarbose is a pseudotetrasaccharide derived from Actinoplanes species, used as an oral alpha-glucosidase inhibitor in the treatment of type 2 diabetes. It delays carbohydrate digestion and absorption in the intestine. The USP standard facilitates assay precision and impurity profiling by chromatographic analysis.

The USP biologics carbohydrates category includes a variety of carbohydrate-based substances that are essential in the development and manufacturing of therapeutic products. These carbohydrates play crucial roles in biological processes and are often utilized as excipients, stabilizers, or active ingredients in pharmaceuticals. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of carbohydrate therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

애플리케이션

Acarbose USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Acarbose Tablets

생화학적/생리학적 작용

Modified tetrasaccharide that acts as a reversible α -glucosidase inhibitor.

분석 메모

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

기타 정보

This product is part of the USP Biologics program.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Sales restrictions may apply.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable