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주요 문서

BP1210

Ritonavir

British Pharmacopoeia (BP) Reference Standard

동의어(들):

1,3-Thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate

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About This Item

실험식(Hill 표기법):
C37H48N6O5S2
CAS Number:
Molecular Weight:
720.94
MDL number:
UNSPSC 코드:
41116107
NACRES:
NA.24

Grade

pharmaceutical primary standard

Quality Level

Agency

BP

API family

ritonavir

양식

solid

유통기한

limited shelf life, expiry date on the label

포장

pkg of 100 mg

제조업체/상표

BP

저장 조건

dry at room temperature

색상

off-white

mp

122-126  °C

solubility

ethanol: soluble
isopropanol: soluble
methanol: soluble

density

1.239 g/cm3 at 20 °C

응용 분야

pharmaceutical
pharmaceutical small molecule

형식

neat

배송 상태

ambient

저장 온도

2-8°C

SMILES string

[s]1c(nc(c1)CN(C)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C[C@H](O)[C@@H](NC(=O)OCc4[s]cnc4)Cc3ccccc3)Cc2ccccc2)C(C)C

InChI

1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1

InChI key

NCDNCNXCDXHOMX-XGKFQTDJSA-N

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일반 설명

Ritonavir belongs to the group of protease inhibitors that are widely used in combination with other drugs in the prevention of HIV. Its mode of action involves binding to the active site of the protease enzyme and preventing the further maturation of new viral particles.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

애플리케이션

Ritonavir BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Ritonavir Oral Solution
  • Ritonavir Tablets
  • 포장

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    기타 정보

    Sales restrictions may apply.

    픽토그램

    Exclamation mark

    신호어

    Warning

    유해 및 위험 성명서

    Hazard Classifications

    Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

    Storage Class Code

    11 - Combustible Solids

    WGK

    WGK 3

    Flash Point (°F)

    Not applicable

    Flash Point (°C)

    Not applicable


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    문서 라이브러리 방문

    RP-HPLC method development and validation for simultaneous estimation of Lopinavir and Ritonavir in tablet dosage form
    Bindu MJ, et al.
    International Journal of Science and Engineering Applications, 5(1), 77-77 (2017)
    HPTLC method for simultaneous determination of lopinavir and ritonavir in capsule dosage form
    Sulebhavikar VA, et al.
    Journal of Chemistry, 5(4), 706-712 (2008)

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