WH0004041M1
Monoclonal Anti-LRP5 antibody produced in mouse
clone 1E9, purified immunoglobulin, buffered aqueous solution
동의어(들):
Anti-BMND1, Anti-HBM, Anti-LR3, Anti-LRP7, Anti-OPPG, Anti-OPS, Anti-VBCH2, Anti-low density lipoprotein receptor-related protein 5
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모든 사진(2)
About This Item
UNSPSC 코드:
12352203
NACRES:
NA.41
추천 제품
생물학적 소스
mouse
Quality Level
결합
unconjugated
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
1E9, monoclonal
양식
buffered aqueous solution
종 반응성
human
기술
ELISA: suitable
western blot: 1-5 μg/mL
동형
IgG1κ
GenBank 수납 번호
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... LRP5(4041)
일반 설명
Low-density lipoprotein receptor-related protein 5 or LRP5 functions as a co-receptor for the Wnt signaling complex. LRP5 is involved in various processes such as bone mass regulation, pulmonary angiogenesis, and alveolar synthesis . Monoclonal Anti-LRP5 antibody is specific for LRP5 in humans.
면역원
LRP5 (NP_002326.1, 41 a.a. ~ 130 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RDVRLVDAGGVKLESTIVVSGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTGAAVQNVVISGLVSPDGLACDWVGKKLYWTDSETN
Sequence
RDVRLVDAGGVKLESTIVVSGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTGAAVQNVVISGLVSPDGLACDWVGKKLYWTDSETN
물리적 형태
Solution in phosphate buffered saline, pH 7.4
법적 정보
GenBank is a registered trademark of United States Department of Health and Human Services
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Yajun Cui et al.
Nature medicine, 17(6), 684-691 (2011-05-24)
The human skeleton is affected by mutations in low-density lipoprotein receptor-related protein 5 (LRP5). To understand how LRP5 influences bone properties, we generated mice with osteocyte-specific expression of inducible Lrp5 mutations that cause high and low bone mass phenotypes in
Tadanori Mammoto et al.
PloS one, 7(7), e41596-e41596 (2012-08-01)
Angiogenesis is crucial for lung development. Although there has been considerable exploration, the mechanism by which lung vascular and alveolar formation is controlled is still not completely understood. Here we show that low-density lipoprotein receptor-related protein 5 (LRP5), a component
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