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Merck
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V3638

Sigma-Aldrich

Vascular Endothelial Growth Factor 164 from rat

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

동의어(들):

VEGF 164, VEGF-164, VEGF164, Vasculotropin

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모든 사진(1)

About This Item

MDL number:
MFCD01636149
UNSPSC 코드:
12352202
NACRES:
NA.32

제품명

Vascular Endothelial Growth Factor 164 from rat, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

생물학적 소스

rat

Quality Level

200

재조합

expressed in NSO cells

분석

>95% (SDS-PAGE)

양식

lyophilized powder

효능

1.08 ng/mL ED50

분자량

dimer 50 kDa by SDS-PAGE
monomer 25 kDa by SDS-PAGE

포장

pkg of 10 μg

저장 조건

avoid repeated freeze/thaw cycles

불순물

endotoxin, tested

UniProt 수납 번호

P16612

저장 온도

−20°C

유전자 정보

rat ... Vegfa(83785)

관련 카테고리

애플리케이션

Vascular Endothelial Growth Factor 164 (VEGF 164) from rat was used for cardiomyocytes culture and Ca2+ transients′ measurement. It was used as a medium M-199 supplement utilized in in vitro incubation for examining the capability of CTS to limit the impact of biologically relevant molecules, in particular epidermal growth factor (EGF), basic fibroblast growth factor (FGF2), and vascular endothelial growth factor A (VEGFA) in rat epididymis segment 1 and 2.

생화학적/생리학적 작용

Mitogen for endothelial cells, enhances vascular permeability, activates, and chemoattracts monocytes and is a procoagulant.
Vascular Endothelial Growth Factor 164 also referred to as VEGF 164 or Vasculotropin is a growth factor that induces endothelial cell growth, vasculogenesis and angiogenesis. VEGF 164 can enhance collagen and fibronectin expression in mesangial cells which in turn stimulates TGF-β1-induced extracellular matrix. It also plays a pivotal role in progressive glomerular fibrosis.

기타 정보

164 amino acid variant of rat VEGF.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in 35% acetonitrile and 0.1% TFA containing 0.5 mg bovine serum albumin.

분석 메모

The biological activity is measured by its ability to stimulate 3H-thymidine incorporation in human umbilical vein endothelial cells.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
SLCJ9173
SLCJ1716
071M1497V
110M1260
050M1589

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문서

Vascular Endothelial Growth Factors (VEGF)

Vascular endothelial growth factor (VEGF) is a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGF-A (VEGF) is a potent growth factor for blood vessel endothelial cells, showing pleiotropic responses that facilitate cell migration, proliferation, tube formation, and survival. In the developing embryo VEGF-A mRNA is expressed by cells within tissues undergoing capillarization.

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