SRP6506

Haptoglobin Plasma (MixedType) from human plasma

≥95% (SDS-PAGE)

• 동의어(들): Bp, Haptoglobin b-Chain, Hp, haptoglobin a-chain
• UNSPSC 코드: 12352202
• NACRES: NA.32

속성

• 생물학적 소스: human plasma
• 분석: ≥95% (SDS-PAGE)
• 양식: lyophilized
• 분자량: monomer 200 kDa (Hp 2-1); monomer 400 kDa (Hp 2-2); monomer 86 kDa (Hp 1-1)
• 포장: pkg of 1 mg
• UniProt 수납 번호: P00738
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: human ... HP(3240)

설명

일반 설명

An acute-phase plasma protein found in human plasma at 100-300 mg/100 mL. Binds hemoglobin, thus preventing loss of iron through the kidneys. Humans are polymorphic for haptoglobin, with three major phenotypes: Hp 1-1, Hp 2-1, and Hp 2-2. While the phenotypic distribution can vary greatly between ethnicities and geographic location, the Hp 2-1 phenotype is the most prevalent phenotype in humans. Plasma concentrations of haptoglobin are highest in individuals with Hp 1-1, intermediate in Hp 2-1 individuals, and lowest in Hp 2-2 individuals. Hp 1-1 is the most effective at binding hemoglobin, and Hp 2-2 is the least effective. This functional difference may be associated with the frequency and severity of epilepsy attacks, as researchers have found a correlation between recurring seizures and the Hp 2-2 phenotype.

물리적 형태

Lyophilized as a salt-free solid.

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable