생물학적 소스
human
재조합
expressed in baculovirus infected Sf9 cells
분석
≥50% (SDS-PAGE)
양식
aqueous solution
분자량
115 kDa
포장
pkg of 20 μg
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−70°C
유전자 정보
human ... RNF20(56254)
일반 설명
Human ring finger protein 20, or RNF20 (GenBank Accession No. NM_019592) full length, amino acids 2-975 (end) with N-terminal His-Flag-tag, MW=115 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
물리적 형태
Formulated in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 80 ng/uL Flag peptide, 20% glycerol and 3 mM DTT.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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시험 성적서(COA)
Lot/Batch Number
Yosef Shiloh et al.
FEBS letters, 585(18), 2795-2802 (2011-08-11)
The DNA damage response (DDR) is emerging as a vast signaling network that temporarily modulates numerous aspects of cellular metabolism in the face of DNA lesions, especially critical ones such as the double strand break (DSB). The DDR involves extensive
Efrat Shema et al.
Molecular cell, 42(4), 477-488 (2011-05-21)
hBRE1/RNF20 is the major E3 ubiquitin ligase for histone H2B. RNF20 depletion causes a global reduction of monoubiquitylated H2B (H2Bub) levels and augments the expression of growth-promoting, pro-oncogenic genes. Those genes reside preferentially in compact chromatin and are inefficiently transcribed
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