SML3951

NSC255112

≥90% (HPLC)

• 동의어(들): NSC255112, 19-[(4-Morpholinylimino)methyl]-geldanamycin, NSC 255112
• 실험식(Hill 표기법): C₃₄H₄₈N₄O₁₀
• CAS Number: 65764-43-4
• Molecular Weight: 672.77
• UNSPSC 코드: 12352200

속성

• Quality Level: 100
• 분석: ≥90% (HPLC)
• 양식: powder
• 색상: , Light red to dark purple
• solubility: DMSO: 2 mg/mL, clear (Warmed)
• 저장 온도: -10 to -25°C
• SMILES string: O=C(C(NC(/C(C)=C/C=C\[C@H](OC)[C@H]1OC(N)=O)=O)=C2/C=N/N3CCOCC3)C(C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C1\C)=C(OC)C2=O
• InChI: 1S/C34H48N4O10/c1-19-15-23-29(40)27(24(30(41)32(23)46-7)18-36-38-11-13-47-14-12-38)37-33(42)20(2)9-8-10-25(44-5)31(48-34(35)43)22(4)17-21(3)28(39)26(16-19)45-6/h8-10,17-19,21,25-26,28,31,39H,11-16H2,1-7H3,(H2,35,43)(H,37,42)/b10-8-,20-9-,22-17-,36-18+/t19
• InChI key: NBLSLHGULNLUQD-PRIZTHDISA-N

설명

생화학적/생리학적 작용

Cell penetrant and potent global inhibitor of cellular glycosylation that induces reversible Golgi fragmentation.
NSC255112 is a cell penetrant and potent global inhibitor of cellular glycosylation that induces reversible Golgi fragmentation. NSC80997 affects both initiation and elongation of O-glycosylation in ways not directly dependent on GalNAc-T11. NSC255112 induces Tn antigen expression in human cell lines. It also reduces cell surface heparan sulfate a necessary factor for SARS-CoV-2 infection.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable