SML3736

Hypoxia probe 2

95% (UPLC)

• 동의어(들): 5’-Methoxy-1’,2’-dimethyl-3-(1-((3-oxo-3H-phenoxazin-7-yl)oxy)ethyl)-1H-indole-4’,7’-dione
• 실험식(Hill 표기법): C₂₅H₂₀N₂O₆
• Molecular Weight: 444.44
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: 95% (UPLC)
• 양식: powder
• 저장 조건: protect from light
• 색상: , Faint orange to red
• solubility: DMSO: 2 mg/mL, clear (Warmed)
• 배송 상태: wet ice
• 저장 온도: -10 to -25°C

설명

생화학적/생리학적 작용

Hypoxia probe 2 is a resorufin-based non-fluorescent hypoxia probe that undergoes cytochrome P450 reductase (PH51)-catalyzed reduction to yield the fluorescent reporter resorufin (ex 545 nm, em 582 nm) in conditions of 4% O2 and lower, allowing imaging hypoxia levels similar to those detected by pimonidazole without the use of antibodies. When employed together with Tokyo green-based hypoxia probe 4 (Tokyo green ex 480 nm, em 515 nm), the probe pair allows the simultaneous (two-color) imaging of different hypoxia levels in living cells.

Resorufin-based hypoxia probe that allows fluorescent imaging of hypoxia levels in live cells similar to those detected by pimonidazole without the use of antibodies.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable