SML3714

SMIP004-7

≥98% (HPLC)

• 동의어(들): 2-Methyl-4-butylaniline, 4-Butyl-2-methylaniline, 4-Butyl-2-methylbenzenamine
• 실험식(Hill 표기법): C₁₁H₁₇N
• CAS Number: 72072-16-3
• Molecular Weight: 163.26
• MDL number: MFCD00190660
• UNSPSC 코드: 12352200
• NACRES: NA.21

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: (Oil or liquid)
• 색상: colorless to brown
• 저장 온도: -10 to -25°C
• SMILES string: Nc1c(cc(cc1)CCCC)C
• InChI key: JTXOXRXZCAMPHL-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

SMIP004-7 is a cell penetrant, potent and selective ubiquinone uncompetitive inhibitor of mitochondrial Complex I (NADH:ubiquinone oxidoreductase). SMIP004-7 selectively binds to a distinct N-terminal region of Complex I catalytic subunit NDUFS2, which leads to rapid disassembly of Complex I. SMIP004-7 potently inhibits growth of triple-negative breast cancer xenografts in mice.

cell penetrant, potent and selective ubiquinone uncompetitive inhibitor of mitochondrial Complex I

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable