SML3575

TY-51469

≥98% (HPLC)

• 동의어(들): 2-[4-[[(5-Fluoro-3-methylbenzo[b]thien-2-yl)sulfonyl]amino]-3-(methylsulfonyl)phenyl]-4-thiazolecarboxylic acid, TY 51469
• 실험식(Hill 표기법): C₂₀H₁₅FN₂O₆S₄
• CAS Number: 603987-59-3
• Molecular Weight: 526.60
• MDL number: MFCD16628177
• UNSPSC 코드: 12352200
• NACRES: NA.21

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: FC1=CC2=C(C=C1)SC(S(NC3=CC=C(C=C3S(C)(=O)=O)C4=NC(C(O)=O)=CS4)(=O)=O)=C2C
• InChI key: CBRCULCCRGSSLB-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Potent and selective chymase inhibitor that prevents development and progression of non-alcoholic steatohepatitis in rats

TY-51469 is a potent and selective chymase inhibitor that prevents development and progression of non-alcoholic steatohepatitis in rats. TY-51469 inhibits activation of intestinal MMP-9 and prevents intestinal damage in indomethacin-induced small intestinal damage in rats. Also TY-51469 might protect against pancreatic islet disorganization.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable