SML3450

PA-8

≥95% (HPLC)

• 동의어(들): 2-​Amino-​5,​8-​dihydro-​5-​[3-​methoxy-​4-​(2-​propen-​1-​yloxy)​phenyl]​-pyrido[2,​3-​d]​pyrimidine-​4,​7(3H,​6H)​-​dione, PA 8
• 실험식(Hill 표기법): C₁₇H₁₈N₄O₄
• CAS Number: 878437-15-1
• Molecular Weight: 342.35
• MDL number: MFCD07400226
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: -10 to -25°C

설명

생화학적/생리학적 작용

PA-8 is a potent and selective PACAP type I (PAC1) receptor agonist that inhibits the phosphorylation of CREB induced by PACAP in PAC1- receptor-expressing CHO cells. PA-8 blocks PACAP-induced aversive responses and mechanical allodynia in mice.

Potent and selective PACAP type I (PAC1) receptor antagonist.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable