SML3381

10-Hydroxy-trans-2-decenoic acid

≥98% (HPLC)

• 동의어(들): (E)-10-Hydroxy-2-decenoic acid, 10-HAD, NSC 87516, Royal jelly acid, Trans-10-hydroxy-2-decenoic acid
• 실험식(Hill 표기법): C₁₀H₁₈O₃
• CAS Number: 14113-05-4
• Molecular Weight: 186.25
• MDL number: MFCD00204506
• UNSPSC 코드: 12352106

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: −20°C
• SMILES string: OCCCCCCC\C=C\C(=O)O
• InChI: 1S/C10H18O3/c11-9-7-5-3-1-2-4-6-8-10(12)13/h6,8,11H,1-5,7,9H2,(H,12,13)/b8-6+
• InChI key: QHBZHVUGQROELI-SOFGYWHQSA-N

설명

생화학적/생리학적 작용

10-Hydroxy-2-decenoic acid is an orally available royal jelly component that potently inhibits osteoclastogenesis. It binds to free fatty acid receptor 4 (FFAR4) on osteoclasts which inhibits RANKL (receptor activator of nuclear factor-κB (NF-κB) ligand), thereby attenuating the induction of nuclear factor of activated T cells (NFAT) c1. 10-Hydroxy-2-decenoic acid inhibits bone resorption in ovariectomized mice.

Royal jelly component that potently inhibits osteoclastogenesis

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable