SML3236

UNC10201652

≥98 mg/mL (HPLC)

• 동의어(들): 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4′,5′:4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine, 1,2,3,4-Tetrahydro-5-(4-morpholinyl)-8-(1-piperazinyl)[1,2,3]triazino[4′,5′:4,5]thieno[2,3-c]isoquinoline
• 실험식(Hill 표기법): C₂₀H₂₅N₇OS
• CAS Number: 372495-52-8
• Molecular Weight: 411.52
• UNSPSC 코드: 12352107
• NACRES: NA.77

속성

• 양식: powder
• Quality Level: 100
• 농도: ≥98 mg/mL (HPLC)
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: C12=C(N3CCOCC3)N=C(SC4=C5N=NN=C4N6CCNCC6)C5=C1CCCC2
• InChI key: ZPVQONCMKZBGTB-UHFFFAOYSA-N

설명

일반 설명

UNC10201652 is a potent and substrate-dependent slow-binding inhibitor of bacterial β-glucuronidases (GUSs) in the gut. UNC10201652 appears to target a catalytic intermediate. It alleviates irinotecan-induced gut damage in mouse models of cancer.

생화학적/생리학적 작용

potent and selective slow binding inhibitor microbiome β-glucuronidase enzyme

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable