SML3204

Dapansutrile

≥98% (HPLC)

• 동의어(들): 3-(Methylsulfonyl)propanenitrile; 3-(Methylsulfonyl)propionitrile, Dapansutrile
• 실험식(Hill 표기법): C₄H₇NO₂S
• CAS Number: 54863-37-5
• Molecular Weight: 133.17
• MDL number: MFCD11934305
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: −20°C
• SMILES string: O=S(C)(CCC#N)=O
• InChI key: LQFRYKBDZNPJSW-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Dapansutrile is an orally active, specific and potent inhibitor of NLRP3 inflammasome activation that decreases IL-1β and IL-18 release. Dapansutrile exhibits no effect on NLRC4 and AIM2 inflammasomes activation. It appears that Dapansutrile directly interact with NLRP3. It does not show hematological, or organ toxicities in humans at oral doses up to 1,000 mg/day

orally active, specific and potent inhibitor of NLRP3 inflammasome activation; anti-inflammatory

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable