SML3197

CA77.1

≥98% (HPLC)

• 동의어(들): N-(4-(6-chloroquinoxalin-2-yl)phenyl)acetamide, N-[4-(6-Chloro-2-quinoxalinyl)phenyl]-acetamide
• 실험식(Hill 표기법): C₁₆H₁₂ClN₃O
• CAS Number: 2412270-22-3
• Molecular Weight: 297.74
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear (warmed)
• 저장 온도: 2-8°C
• SMILES string: Clc1cc2ncc(nc2cc1)c3ccc(cc3)NC(=O)C
• InChI: 1S/C16H12ClN3O/c1-10(21)19-13-5-2-11(3-6-13)16-9-18-15-8-12(17)4-7-14(15)20-16/h2-9H,1H3,(H,19,21)
• InChI key: ZQXMPDVGBWOTBY-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

CA77.1 is an orally available, brain penetrant, in vivo active and potent enhancer of chaperone-mediated autophagy (CMA). It improves pathology in Alzheimer′s Disease mouse models. CA77.1 activates CMA in vitro without affecting macroautophagy.

orally available, brain penetrant, in vivo active and potent enhancer of chaperone-mediated autophagy (CMA)

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable