SML3014

KL101

≥98% (HPLC)

• 동의어(들): N-(2-(2,4-Dimethylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl)-3,4-dimethyl-benzamide
• 실험식(Hill 표기법): C₂₂H₂₃N₃OS
• CAS Number: 396721-89-4
• Molecular Weight: 377.50
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: CC1=CC=C(C(NC2=C(CSC3)C3=NN2C4=C(C)C=C(C)C=C4)=O)C=C1C
• InChI: 1S/C22H23N3OS/c1-13-5-8-20(16(4)9-13)25-21(18-11-27-12-19(18)24-25)23-22(26)17-7-6-14(2)15(3)10-17/h5-10H,11-12H2,1-4H3,(H,23,26)
• InChI key: FJKKXWLUKJOWNU-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

KL101 is a circadian clock modulator that lengthens a circadian period in cells and tissues. It selectively stabilizes CRY1 through interaction with FAD-binding pocket. KL101 strongly enhanced brown adipocyte differentiation in culture. KL101 showed no or only minor effects on CKIδ, CKIα and CK2 activities in vitro.

circadian clock modulator that selectively stabilizes CRY1

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable