SML2946
Biotin-aniline
≥98% (HPLC)
동의어(들):
(3aS,4S,6aR)-N-[2-(4-Aminophenyl)ethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide, Btn-An, N-(4-Aminophenethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, N-(4-Aminophenethyl)biotinamide
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C18H26N4O2S
CAS Number:
Molecular Weight:
362.49
UNSPSC 코드:
12352200
NACRES:
NA.77
추천 제품
Quality Level
분석
≥98% (HPLC)
양식
powder
색상
white to beige
solubility
DMSO: 2 mg/mL, clear
저장 온도
2-8°C
SMILES string
O=C(CCCC[C@@H]1SC[C@]([H])(N2)[C@@]1(NC2=O)[H])NCCC3=CC=C(C=C3)N
InChI
1S/C18H26N4O2S/c19-13-7-5-12(6-8-13)9-10-20-16(23)4-2-1-3-15-17-14(11-25-15)21-18(24)22-17/h5-8,14-15,17H,1-4,9-11,19H2,(H,20,23)(H2,21,22,24)/t14-,15-,17-/m0/s1
InChI key
AHRRICHWBPPWDZ-ZOBUZTSGSA-N
생화학적/생리학적 작용
A superior substrate than biotinyl tyramide (biotin-phenol; BP) for APEX2-mediated proximity-labeling of RNA.
Biotin-aniline (Btn-An) is a superior substrate than biotinyl tyramide (biotin-phenol; BP) for APEX2-mediated proximity labeling of RNA (∼25-fold higher by dot blot with 0.5 mM substrate and 0.4-10 μg RNA/dot). Btn-An specifically labels mitochondrial, but not cytoplasmic, mRNAs in live HEK293T stable line expressesing APEX2 in the mitochondrial matrix (mito-APEX2).
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Ying Zhou et al.
Angewandte Chemie (International ed. in English), 58(34), 11763-11767 (2019-06-27)
The subcellular organization of biomolecules such as proteins and nucleic acids is intimately linked to their biological functions. APEX2, an engineered ascorbate peroxidase that enables proximity-dependent labeling of proteins in living cells, has emerged as a powerful tool for deciphering
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