SML2810

Prostetin Trifluoroacetic acid salt

≥98% (HPLC)

• 동의어(들): 2-(4-(4-(3-(3-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)benzyl)piperazin-1-yl)ethan-1-ol Trifluoroacetic acid salt, 2-(4-(4-(3-(3-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)benzyl)piperazin-1-yl)ethanol Trifluoroacetic acid salt, 4-[[4-[3-(3-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]phenyl]methyl]-1-piperazineethanol Trifluoroacetic acid salt
• 실험식(Hill 표기법): C₂₆H₂₇ClN₄O · xC₂HF₃O₂
• Molecular Weight: 446.97 (free base basis)
• UNSPSC 코드: 12352106
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: 2-8°C

설명

생화학적/생리학적 작용

Prostetin is an orally available, blood-brain barrier-penetrant, potent and metabolically stable inhibitor of the mitogen-activated protein kinase kinase kinase kinase (MAP4K, or HGK) that exhibits neuroprotective and anti-inflammatory properties. Prostetin is more potent than URMC-099 in motor neuron survival assay. Prostetin rescues CPA-induced neurodegeneration in motor neurons.

orally available, blood-brain barrier-penetrant, potent and metabolically stable inhibitor of MAP4K (HGK) that exhibits neuroprotective properties

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable