SML2670

BAY-8002

≥98% (HPLC)

• 동의어(들): 2-(2-chloro-5-(phenylsulfonyl)benzamido)benzoic acid, 2-[[2-Chloro-5-(phenylsulfonyl)benzoyl]amino]-benzoic acid
• 실험식(Hill 표기법): C₂₀H₁₄ClNO₅S
• CAS Number: 724440-27-1
• Molecular Weight: 415.85
• MDL number: MFCD05157149
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: [S](=O)(=O)(c2cc(c(cc2)Cl)C(=O)Nc3c(cccc3)C(=O)O)c1ccccc1
• InChI: 1S/C20H14ClNO5S/c21-17-11-10-14(28(26,27)13-6-2-1-3-7-13)12-16(17)19(23)22-18-9-5-4-8-15(18)20(24)25/h1-12H,(H,22,23)(H,24,25)
• InChI key: CLAUJSRBKSRTGQ-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

BAY-8002 is an orally available, potent and selective inhibitor of lactate transporter MCT1 (monocarboxylate transporter 1; SLC16A1) that potently inhibits bidirectional lactate transport. BAY-8002 exhibits antiproliferative activity in numerous cancer cell lines. BAY-8002 induces accumulation of lactate and significantly inhibits tumor growth in mice model. It does not cause tumor regression.

orally available, potent and selective inhibitor of lactate transporter MCT1

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable