SML2503

Pellitorine

≥97% (HPLC)

• 동의어(들): (2E,4E)-N-(2-Methylpropyl)-2,4-decadienamide, (2E,4E)-N-Isobutyl-2,4-decadienamide, 2E,4E-Decadienoic acid N-isobutylamide, trans-Pellitorin, trans-Pellitorine
• 실험식(Hill 표기법): C₁₄H₂₅NO
• CAS Number: 18836-52-7
• Molecular Weight: 223.35
• MDL number: MFCD01735995
• UNSPSC 코드: 51111800
• NACRES: NA.77

속성

• 분석: ≥97% (HPLC)
• 양식: powder
• 저장 조건: desiccated
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: −20°C
• SMILES string: N(CC(C)C)C(=O)\C=C\C=C\CCCCC
• InChI: 1S/C14H25NO/c1-4-5-6-7-8-9-10-11-14(16)15-12-13(2)3/h8-11,13H,4-7,12H2,1-3H3,(H,15,16)/b9-8+,11-10+
• InChI key: MAGQQZHFHJDIRE-BNFZFUHLSA-N

설명

생화학적/생리학적 작용

ACAT inhibitor; α-Glucosidase inhibitor; anti-inflammatory;

Pellitorine is an α-Glucosidase inhibitor isolated from the roots of Piper Nigrum that exhibit anti-diabetic, anti-cancer, anti-bacterial and anti-inflammatory properties. Pellitorine is an ACAT (Acyl-CoA cholesteryl acyl transferase) inhibitor that inhibits cholesterol esterification in HepG2 cells. Also pellitorine exhibit potent larvicide activity in mosquito by Inhibition of gene expression encoding V-type H+-ATPase and aquaporine 4. Some new research suggests that anti-adipogenic activity of pellitorine depends on TRPV1.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable