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Merck
모든 사진(1)

주요 문서

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SML2485

Sigma-Aldrich

Marbofloxacin

≥98% (HPLC)

동의어(들):

9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[3,2,1-ij][4,1,2]benzoxadiazine-6-carboxylic acid, Aurizon, Marbocyl, Zeniquin, 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-piperazino)-7-oxo-7H-pyrido[1,2,3-ij][1,2,4]benzoxadiazine-6-carboxylic acid, Zeniquin®

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C17H19FN4O4
CAS Number:
115550-35-1
Molecular Weight:
362.36
MDL number:
MFCD00864820
UNSPSC 코드:
12352200
NACRES:
NA.77

분석

≥98% (HPLC)

양식

powder

색상

white to beige

solubility

DMSO: 2 mg/mL, clear (warmed)

저장 온도

2-8°C

SMILES string

CN1CCN(CC1)c2c(F)cc3C(=O)C(=CN4N(C)COc2c34)C(O)=O

InChI

1S/C17H19FN4O4/c1-19-3-5-21(6-4-19)14-12(18)7-10-13-16(14)26-9-20(2)22(13)8-11(15(10)23)17(24)25/h7-8H,3-6,9H2,1-2H3,(H,24,25)

InChI key

BPFYOAJNDMUVBL-UHFFFAOYSA-N

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생화학적/생리학적 작용

Marbofloxacin is a broad-spectrum fluoroquinolone antibiotic active against both Gram-negative and Gram-positive bacteria. It is believed to act by impairing the bacterial DNA gyrase. Marbofloxacin has also been shown to exhibit antileishmanial activity in a canine model.

법적 정보

Zeniquin is a registered trademark of Pfizer, Inc.

유해 및 위험 성명서

H412

예방조치 성명서

P273 - P501

Hazard Classifications

Aquatic Chronic 3

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Marilisa Novacco et al.
Veterinary microbiology, 217, 112-120 (2018-04-05)
Mycoplasma haemofelis is the most pathogenic feline hemoplasma species and a causative agent of infectious hemolytic anemia in cats. Current treatment protocols are effective in reducing M. haemofelis blood loads and clinical signs but consistent bacteremia clearance is rarely achieved.
Carmen Pineda et al.
PloS one, 12(10), e0185981-e0185981 (2017-10-06)
Treatment of canine leishmaniasis (CanL) represents a challenge. Due to the high prevalence of renal disease associated to CanL, it is important to find an effective drug that does not damage the kidneys. Marbofloxacin has been shown to be effective
M Spreng et al.
Journal of veterinary pharmacology and therapeutics, 18(4), 284-289 (1995-08-01)
Marbofloxacin is a new fluoroquinolone developed exclusively for veterinary use. Minimum inhibitory concentrations of marbofloxacin were assessed for 816 recent isolates associated with canine or feline diseases. Marbofloxacin showed a broad spectrum of activity against gram-negative and gram-positive bacteria. In

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