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Merck
모든 사진(1)

주요 문서

SML2424

Sigma-Aldrich

Terlipressin acetate salt

≥98% (HPLC)

동의어(들):

H-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-GlyNH2 acetate salt (Disulfide bond), N-(glycylglycylglycyl)-8-L-lysine-vasopressin acetate salt

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C52H74N16O15S2 · xC2H4O2
CAS Number:
914453-96-6
Molecular Weight:
1227.37 (free base basis)
UNSPSC 코드:
12352200
NACRES:
NA.77

분석

≥98% (HPLC)

양식

lyophilized powder

저장 조건

desiccated

색상

white

배송 상태

wet ice

저장 온도

−20°C

SMILES string

S1SC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](C1)C(=O)N4[C@@H](CCC4)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N)Cc3ccccc3)Cc2ccc(cc2)O)NC(=O)CNC(=O)CNC(=O)CN.OC(=O)C.OC(=O)C

InChI

1S/C52H74N16O15S2.2C2H4O2/c53-17-5-4-9-31(45(76)60-23-41(57)72)63-51(82)38-10-6-18-68(38)52(83)37-27-85-84-26-36(61-44(75)25-59-43(74)24-58-42(73)22-54)50(81)65-34(20-29-11-13-30(69)14-12-29)48(79)64-33(19-28-7-2-1-3-8-28)47(78)62-32(15-16-39(55)70)46(77)66-35(21-40(56)71)49(80)67-37;2*1-2(3)4/h1-3,7-8,11-14,31-38,69H,4-6,9-10,15-27,53-54H2,(H2,55,70)(H2,56,71)(H2,57,72)(H,58,73)(H,59,74)(H,60,76)(H,61,75)(H,62,78)(H,63,82)(H,64,79)(H,65,81)(H,66,77)(H,67,80);2*1H3,(H,3,4)/t31-,32-,33-,34-,35-,36-,37-,38-;;/m0../s1

InChI key

WNFVFDPQEHRNTC-LWCZBKQBSA-N

생화학적/생리학적 작용

Synthetic vasopressin analog and agonist
Terlipressin is a synthetic vasopressin analog and agonist. It has been used as a vasoactive drug for treatment of Hepatorenal syndrome in cirrhosis of the liver.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Tim G Kampmeier et al.
Scientific reports, 8(1), 7105-7105 (2018-05-10)
The Surviving Sepsis Guidelines suggest the use of vasopressin in case of catecholamine-refractory septic shock. Terlipressin (TP) as a V1-selective AVP analogue is a potential alternative, though data regarding the first-line administration in septic shock are scarce. The present study
Timothy Papaluca et al.
Journal of gastroenterology and hepatology, 33(3), 591-598 (2017-10-06)
Terlipressin is an analogue of vasopressin that has potent vasoactive properties and has been available for use in most countries for nearly two decades. It has both established roles and emerging indications in the management of complications of decompensated chronic
K K Ida et al.
British journal of anaesthesia, 120(6), 1245-1254 (2018-05-26)
During early treatment of haemorrhagic shock, cerebral perfusion pressure can be restored by small-volume resuscitation with vasopressors. Whether this therapy is improved with additional fluid remains unknown. We assessed the value of terlipressin and lactated Ringer's solution (LR) on early

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