SML1432

PHCCC

≥97% (HPLC)

• 동의어(들): 7,7a-Dihydro-7-(hydroxyimino)-N-phenyl-benzo[b]cyclopropa[e]pyran-1a(1H)-carboxamide, N-Phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide
• 실험식(Hill 표기법): C₁₇H₁₄N₂O₃
• CAS Number: 179068-02-1
• Molecular Weight: 294.30
• UNSPSC 코드: 12352202
• PubChem Substance ID: 329825873
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥97% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 10 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: O=C(NC1=CC=CC=C1)C2(C/3C2)OC4=C(C=CC=C4)C3=N/O
• InChI: 1S/C17H14N2O3/c20-16(18-11-6-2-1-3-7-11)17-10-13(17)15(19-21)12-8-4-5-9-14(12)22-17/h1-9,13,21H,10H2,(H,18,20)/b19-15+
• InChI key: FPXPIEZPAXSELW-XDJHFCHBSA-N

설명

생화학적/생리학적 작용

PHCCC is a positive allosteric modulator (PAM) at the mGluR4 subtype that exhibits anxiolytic and anti-Parkinsonian effects in animal models. PHCCC is a potent group I metabotropic glutamate receptor antagonist.

PHCCC is a positive allosteric modulator (PAM) at the mGluR4 subtype. PHCCC is a potent group I metabotropic glutamate receptor antagonist.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable