SML1152

GSK137647A

≥98% (HPLC)

• 동의어(들): 4-Methoxy-N-(2,4,6-trimethylphenyl)-benzenesulfonamide, N-Mesityl-4-methoxybenzenesulfonamide
• 실험식(Hill 표기법): C₁₆H₁₉NO₃S
• CAS Number: 349085-82-1
• Molecular Weight: 305.39
• MDL number: MFCD02007969
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825685
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 20 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: CC1=C(NS(C2=CC=C(OC)C=C2)(=O)=O)C(C)=CC(C)=C1
• InChI: 1S/C16H19NO3S/c1-11-9-12(2)16(13(3)10-11)17-21(18,19)15-7-5-14(20-4)6-8-15/h5-10,17H,1-4H3
• InChI key: FQUAFMNPXPXOJE-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

GSK137647A is a selective agonist of the free fatty acid receptor 4 (FFA4/GPR120), which is involved in long-chain fatty acid stimulated GLP-1 secretion and has been implicated in glucose homeostasis, adiposity, and regulation of the anti-inflammatory response. GSK137647A has pEC₅₀ values of 6.3, 6.2, and 6.1 for human, mouse and rat FFA4, and pEC₅₀ values < 4.5 for all three species for FFA1, FFA2, and FFA3.

GSK137647A is a selective agonist of the free fatty acid receptor 4 (FFA4/GPR120).

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable