SML0866

BMS-191011

≥98% (HPLC)

• 동의어(들): 3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2(3H)-one
• 실험식(Hill 표기법): C₁₆H₁₀ClF₃N₂O₃
• CAS Number: 202821-81-6
• Molecular Weight: 370.71
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 20 mg/mL, clear (warmed)
• 저장 온도: room temp
• SMILES string: FC(F)(F)c1ccc(cc1)C2=NN(C(=O)O2)Cc3c(ccc(c3)Cl)O
• InChI: 1S/C16H10ClF3N2O3/c17-12-5-6-13(23)10(7-12)8-22-15(24)25-14(21-22)9-1-3-11(4-2-9)16(18,19)20/h1-7,23H,8H2
• InChI key: QKOWACXSXTXRKA-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

BMS-191011 is a potent opener of BKCa opener (large-conductance Ca2+-activated K channel).

BMS-191011 is a potent opener of BKCa opener (large-conductance Ca2+-activated K channel). The compound BMS-191011 has neuroprotective properties in rodent models of stroke, and induces dialation of rat retinal arterioles.

특징 및 장점

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301,H413
• 예방조치 성명서: P264 - P270 - P273 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Chronic 4
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable