SML0461

PH-002

≥98% (HPLC)

• 동의어(들): 4-[[4-[[2-(3,4-Dihydro-3-methyl-4-oxo-1-phthalazinyl)acetyl]amino]phenyl]methyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester, PH 002, PH002
• 실험식(Hill 표기법): C₂₇H₃₃N₅O₄
• CAS Number: 1311174-68-1
• Molecular Weight: 491.58
• MDL number: MFCD22666400
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329824739
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 10 mg/mL (clear solution)
• 저장 온도: 2-8°C
• SMILES string: O=C(N1CCN(CC2=CC=C(NC(CC3=NN(C)C(C4=C3C=CC=C4)=O)=O)C=C2)CC1)OC(C)(C)C
• InChI: 1S/C27H33N5O4/c1-27(2,3)36-26(35)32-15-13-31(14-16-32)18-19-9-11-20(12-10-19)28-24(33)17-23-21-7-5-6-8-22(21)25(34)30(4)29-23/h5-12H,13-18H2,1-4H3,(H,28,33)
• InChI key: GSXXTLWPQMHHDJ-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

PH-002 is an inhibitor of apolipoprotein (apo) E4 intramolecular domain interaction in neuronal cells that restores mitochondrial cytochrome c oxidase subunit 1 levels, rescues impairments of mitochondrial motility and neurite outgrowth. PH-002 is an apoE4 structure corrector that reverses the apoE4 detrimental effects.

PH-002 is an inhibitor of apolipoprotein (apo) E4 intramolecular domain interaction; apoE4 structure corrector.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable