SML0148

Imidapril hydrochloride

≥98% (HPLC)

• 동의어(들): (4S)-3-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic acid hydrochloride, Novaloc, TA 6366, Tanapril
• 실험식(Hill 표기법): C₂₀H₂₇N₃O₆ · HCl
• CAS Number: 89396-94-1
• Molecular Weight: 441.91
• MDL number: MFCD00923828
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825196
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 광학 활성: [α]/D -50 to -70° in ethanol (c=0.5)
• 색상: white to tan
• solubility: H₂O: ≥5 mg/mL
• 주관자: Trinity Pharma Solutions
• 저장 온도: −20°C
• SMILES string: Cl.CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2[C@@H](CN(C)C2=O)C(O)=O
• InChI: 1S/C20H27N3O6.ClH/c1-4-29-19(27)15(11-10-14-8-6-5-7-9-14)21-13(2)17(24)23-16(18(25)26)12-22(3)20(23)28;/h5-9,13,15-16,21H,4,10-12H2,1-3H3,(H,25,26);1H/t13-,15-,16-;/m0./s1
• InChI key: LSLQGMMMRMDXHN-GEUPQXMHSA-N

설명

일반 설명

Imidapril comprises large acyl moiety and is hydrolyzed by carboxylesterase (CES) 1.

애플리케이션

Imidapril hydrochloride may be used to test its effect on pharyngeal and laryngeal muscle to treat impaired swallowing.

Imidapril hydrochloride was used as a standard in bioequivalence test by LC/MS method.

생화학적/생리학적 작용

Angiotensin Converting Enzyme (ACE) inhibitor

Imidapril hydrochloride is a long-acting inhibitor of angiotensin converting enzyme used in the treatment of hypertension, congestive heart failure and diabetic nephropathy. It restores decreased airway sensation and bladder sensation in patients with multiple sclerosis.

Imidapril is a potent angiotensin converting enzyme inhibitor and anti-hypertensive.

특징 및 장점

This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Trinity Pharma Solutions. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable