SBR00097

Sancycline

≥95% (H-NMR), powder

• 동의어(들): 6-Demethyl-6-deoxytetracycline, Bonomycin, Norcycline
• 실험식(Hill 표기법): C₂₁H₂₂N₂O₇
• CAS Number: 808-26-4
• Molecular Weight: 414.41
• UNSPSC 코드: 51101500

속성

• Quality Level: 100
• 분석: ≥95% (H-NMR)
• 양식: powder
• 색상: yellow to brown
• 항생제 활성 스펙트럼: Gram-negative bacteria; Gram-positive bacteria; mycoplasma
• 동작 모드: protein synthesis | inhibits
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: CN(C)[C@H]1[C@@H]2C[C@@H]3CC4=C(C(=CC=C4)O)C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O
• InChI: 1S/C21H22N2O7/c1-23(2)15-10-7-9-6-8-4-3-5-11(24)12(8)16(25)13(9)18(27)21(10,30)19(28)14(17(15)26)20(22)29/h3-5,9-10,15,24-25,28,30H,6-7H2,1-2H3,(H2,22,29)/t9-,10-,15-,21-/m0/s1
• InChI key: MTCQOMXDZUULRV-ADOAZJKMSA-N

설명

일반 설명

Sancycline is an antibioitic which belongs to the class of compounds known as tetracycline antibiotics. It is a semisynthetic derivative of naturally occurring tetracycline and is used in the treatment of bacterial infections caused by susceptible organisms. Sancycline is active against a wide range of Gram-positive and Gram-negative bacteria, as well as atypical bacteria such as Mycoplasma and Chlamydia species.

생화학적/생리학적 작용

Sancycline inhibits bacterial protein synthesis by binding to the 30S subunit of the bacterial ribosome. Specifically, it binds to the A site of the ribosome and blocks the attachment of aminoacyl-tRNA molecules to the ribosome, which is necessary for the addition of new amino acids to the growing polypeptide chain. This ultimately leads to the inhibition of bacterial protein synthesis and bacterial death.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable