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Merck
모든 사진(1)

주요 문서

SBR00085

Sigma-Aldrich

Orbifloxacin

≥95% (H-NMR), powder

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About This Item

실험식(Hill 표기법):
C19H20F3N3O3
CAS Number:
Molecular Weight:
395.38
UNSPSC 코드:
51101500

Quality Level

분석

≥95% (H-NMR)

양식

powder

색상

off-white to yellow

항생제 활성 스펙트럼

Gram-negative bacteria
Gram-positive bacteria

동작 모드

DNA synthesis | inhibits

저장 온도

2-30°C

SMILES string

C[C@@H]1CN(C[C@@H](N1)C)C2=C(C3=C(C(=C2F)F)C(=O)C(=CN3C4CC4)C(=O)O)F

InChI

InChI=1S/C19H20F3N3O3/c1-8-5-24(6-9(2)23-8)17-14(21)13(20)12-16(15(17)22)25(10-3-4-10)7-11(18(12)26)19(27)28/h7-10,23H,3-6H2,1-2H3,(H,27,28)/t8-,9+

InChI key

QIPQASLPWJVQMH-DTORHVGOSA-N

일반 설명

Orbifloxacin is a fluoroquinolone antibiotic which inhibits bacterial growth by inhibiting DNA gyrase and topoisomerase IV.

애플리케이션

Orbifloxacin has very limited non-medical applications, as it is primarily known and used as a veterinary antibiotic for the treatment of bacterial infections in animals. However, it can be used as a reference standard in analytical chemistry for the development and validation of methods for the detection and quantification of fluoroquinolone antibiotics, such as Orbifloxacin, in various samples, such as food, environmental, and biological samples. Orbifloxacin has been used as a standard for the analysis of fluoroquinolone antibiotics in food products, such as meat, milk, and eggs, as well as in environmental samples, such as water and soil. Moreover, its potential use in animals, particularly livestock and poultry, highlights the importance of prudent use and management of the antibiotic to prevent the development and spread of antibiotic-resistant bacteria.

생화학적/생리학적 작용

Orbifloxacin inhibits bacterial DNA synthesis through interference with the activity of DNA gyrase and topoisomerase IV enzymes, which are necessary for the replication, transcription, and repair of bacterial DNA. Orbifloxacin is active against Gram-negative and Gram-positive bacteria, including many strains of Escherichia coli, Pasteurella, Streptococcus, and Staphylococcus species.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

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