SBR00081

Favipiravir

≥97% (HPLC), powder

• 동의어(들): Favilavir, T-705
• 실험식(Hill 표기법): C₅H₄FN₃O₂
• CAS Number: 259793-96-9
• Molecular Weight: 157.10
• UNSPSC 코드: 51101500

속성

• Quality Level: 100
• 분석: ≥97% (HPLC)
• 양식: powder
• 색상: white to yellow
• 항생제 활성 스펙트럼: viruses
• 동작 모드: enzyme | inhibits
• 저장 온도: −20°C
• SMILES string: C1=C(N=C(C(=O)N1)C(=O)N)F
• InChI: InChI=1S/C5H4FN3O2/c6-2-1-8-5(11)3(9-2)4(7)10/h1H,(H2,7,10)(H,8,11)
• InChI key: ZCGNOVWYSGBHAU-UHFFFAOYSA-N

설명

일반 설명

Favipiravir is a pyrazinecarboxamide derivative which is an RNA polymerase inhibitors. Favipiravir is converted to the ribofuranosyltriphosphate derivative by host enzymes and selectively inhibits the influenza viral RNA-dependent RNA polymerase. Favipiravir has broad-spectrum activity against RNA viruses, including influenza viruses, arena viruses, bunyaviruses, and flaviviruses.

생화학적/생리학적 작용

Favipiravir inhibits the RNA-dependent RNA polymerase enzyme, which is essential for the replication of RNA viruses such as influenza and SARS-CoV-2 (the virus that causes COVID-19). Inhibition of RNA-dependent RNA polymerase activity leads to the disruption of viral RNA replication and ultimately, the reduction of viral load.

안전성 정보

• 픽토그램: GHS08
• 신호어: Warning
• 유해 및 위험 성명서: H341,H361d
• 예방조치 성명서: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Muta. 2 - Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable