SBR00079

Delamanid

≥98% (HPLC), powder

• 동의어(들): OPC-67683
• 실험식(Hill 표기법): C₂₅H₂₅F₃N₄O₆
• CAS Number: 681492-22-8
• Molecular Weight: 534.48
• UNSPSC 코드: 51101500

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 저장 조건: dry media
• 색상: white to off-white
• 항생제 활성 스펙트럼: mycobacteria
• 동작 모드: cell wall synthesis | inhibits
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: C[C@@]1(CN2C=C(N=C2O1)[N+](=O)[O-])COC3=CC=C(C=C3)N4CCC(CC4)OC5=CC=C(C=C5)OC(F)(F)F
• InChI: InChI=1S/C25H25F3N4O6/c1-24(15-31-14-22(32(33)34)29-23(31)38-24)16-35-18-4-2-17(3-5-18)30-12-10-20(11-13-30)36-19-6-8-21(9-7-19)37-25(26,27)28/h2-9,14,20H,10-13,15-16H2,1H3/t24-/m1/s1
• InChI key: XDAOLTSRNUSPPH-XMMPIXPASA-N

설명

일반 설명

Delamanid is an anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid synthesis of bacterial cell wall. A limitation of dasabuvir is the lower potential for cross-genotypic activity as the binding sites are poorly preserved across HCV genotypes.

생화학적/생리학적 작용

Delamanid is an antimycobacterial agent that inhibits mycolic acid synthesis, an essential component of the cell wall of Mycobacterium tuberculosis. Inhibition of mycolic acid synthesis leads to the disruption of cell wall structure and integrity, and ultimately, bacterial cell death.

안전성 정보

• 픽토그램: GHS08
• 신호어: Warning
• 유해 및 위험 성명서: H361d
• 예방조치 성명서: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable