SBR00075

Avibactam Sodium Salt

≥97% (HPLC), powder

• 동의어(들): NXL-104
• 실험식(Hill 표기법): C₇H₁₁N₃NaO₆S
• CAS Number: 1192491-61-4
• Molecular Weight: 288.23
• UNSPSC 코드: 51101500

속성

• Quality Level: 100
• 분석: ≥97% (HPLC)
• 양식: powder
• 저장 조건: under inert gas (Nitrogen)
• 색상: white
• 항생제 활성 스펙트럼: Gram-negative bacteria
• 동작 모드: enzyme | inhibits
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: C1C[C@H](N2C[C@@H]1N(C2=O)OS(=O)(=O)[O-])C(=O)N.[Na+]
• InChI: InChI=1S/C7H11N3O6S.Na/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15;/h4-5H,1-3H2,(H2,8,11)(H,13,14,15);/q;+1/p-1/t4-,5+;/m1./s1
• InChI key: RTCIKUMODPANKX-JBUOLDKXSA-M

설명

일반 설명

Avibactam sodium is a β-lactamase inhibitor and β-Lactamases are responsible for resistance to penicillins, monobactams, carbapenems, and extended-spectrum cephalosporins. It is a synthetic molecule with activity against gram-negative bacteria.

애플리케이션

Avibactam and related compounds have been studied for their ability to inhibit a variety of beta-lactamases, which are enzymes that inactivate beta-lactam antibiotics such as penicillin. The development of new beta-lactamase inhibitors like Avibactam is important for combating antibiotic resistance.

생화학적/생리학적 작용

Avibactam is a β-lactamase inhibitor which inhibits the activity of β-lactamases by binding to the active site of β-lactamases and blocks the access of the substrate to the enzyme. Avibactam is effective against bacteria resistant to ceftazidime like Escherichia coli.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable