SBR00059

Balofloxacin

≥98% (HPLC), powder

• Linear Formula: C₂₀H₂₄FN₃O₄.2H₂O
• CAS Number: 127294-70-6
• UNSPSC 코드: 51101500

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: off-white
• 항생제 활성 스펙트럼: (anaerobic bacteria); Gram-negative bacteria; Gram-positive bacteria
• 동작 모드: DNA synthesis | inhibits
• SMILES string: CNC1CCCN(C1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F
• InChI: 1S/C20H24FN3O4/c1-22-11-4-3-7-23(9-11)17-15(21)8-13-16(19(17)28-2)24(12-5-6-12)10-14(18(13)25)20(26)27/h8,10-12,22H,3-7,9H2,1-2H3,(H,26,27)
• InChI key: MGQLHRYJBWGORO-UHFFFAOYSA-N

설명

일반 설명

Balofloxacin is a broad spectrum synthetic fluoroquinolone antibiotic. It exerts its antibacterial activity by inhibiting DNA gyrase and topoisomerase IV, which are enzymes essential for bacterial DNA synthesis and replication.

애플리케이션

One of the main applications of fluoroquinolones like Balofloxacin is their ability to target and inhibit bacterial DNA gyrase and topoisomerase IV, which are enzymes that are essential for bacterial DNA replication and transcription. Because of their potency against these targets, fluoroquinolones have been used as lead compounds for the development of new antibiotics and other drugs that target these enzymes.

생화학적/생리학적 작용

Balofloxacin inhibits bacterial DNA synthesis by interfering with the activity of DNA gyrase and topoisomerase IV enzymes, which are necessary for the replication, transcription, and repair of bacterial DNA. Balofloxacin is active against gram-negative, gram-positive, and anaerobic bacteria.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable