SAB5600078

Anti-Integrin alpha 4 antibody, Rabbit monoclonal

recombinant, expressed in HEK 293 cells, clone RM268, purified immunoglobulin

• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 재조합: expressed in HEK 293 cells
• Quality Level: 100
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: RM268, monoclonal; recombinant monoclonal
• 양식: buffered aqueous glycerol solution
• 종 반응성: human
• 기술: immunoblotting: 1:1000-1:2000; immunohistochemistry: 1:1000-1:5000
• 동형: IgG
• NCBI 수납 번호: 3676
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... ITGA4(3676)

설명

일반 설명

Integrin subunit α4 (ITGA4) is an adhesive factor, that is part of the integrin family. The gene encoding it is localized on human chromosome 2q31.3.

특이성

This antibody reacts to the cytoplasmic domain of human Integrin alpha 4 (ITGA4).

면역원

Synthetic peptide corresponding to the C-terminus of human Integrin alpha 4 (ITGA4)

생화학적/생리학적 작용

Integrin subunit α 4 (ITGA4) has a role in bone marrow homing. It associates with the β1 integrin chain and forms the very-late-antigen-4 (VLA-4) complex. The protein also binds to vascular cell adhesion molecule-1, fibronectin and osteopontin (OPN) and modulates the activity of immature progenitors in the bone marrow. ITGA4 also aids the migration of B lymphocytes through the fibroblast barrier.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable